HAMES_DBI.A6

 Varsite

Name: sodium/glucose cotransporter 1

ID number: P13866

Uniprot ID: P13866

Tissue details: Lines the absorptive cells in the small intestine and proximal tubes in the kidney in order to uptake glucose in the cells.

Diseases: GGM (Congenital galactose/glucose malabsorption)

Tissue specificity: Expressed mainly in the intestine and kidney

Cofactors: cellular hexose transport, defective SLC5A1 causes congenital glucose/galactose malabsorption (GGM), intestinal hexose transport

Organs/systems of high level of expression: liver, heart, mouth

Organs/system of low level of expression: gonads, brain, pituitary gland

I. Three aspects that I am still curious about with my protein are the specifics of the disease that is caused by its mutation- GGM, it's role in other organisms besides humans, and more information on how it can be regulated by drugs and medication.

II. A potential research project would be looking into gene manipulation/editing and gene expression of SLC5A1 through CRISPR, and how it can correlate to GGM.

Comments

  1. EricaMarch 12, 2022 at 10:09 AM

    I love it!! Keep that reasearch idea in mind moving forward!

    ReplyDelete

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